Bcl-xL prevents apoptosis through two different mechanisms: heterodimerization with an apoptotic protein inhibits its apoptotic effect and formation of mitochondrial outer membrane pores help maintain a normal membrane state under stressful conditions.
Product Name: Bcl-Xl Rabbit Polyclonal Antibody
Isotype: IgG
Storage Buffer : Antigen Affinity Purified IgG in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Storage instructions:-20°C. Do not aliquot the antibody
Recommended dilutions: IHC: 1:50-100
Optimal dilutions should be determined by the end user.
Specificity: Antibody can detects endogenous Bcl-Xl protein.
Alternative Names: B2CL1 antibody, Bcl 2 like 1antibody, Apoptosis regulator Bcl X antibody
Form: Liquid
Reactivity: H, R, M
Molecular Weight: 30KD
Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma using Bcl-Xl (BE3446)Rabbit pAb diluted at 1:200