The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
Product Name:β-Catenin Rabbit Polyclonal Antibody
Isotype: IgG
Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol
Storage instructions:-20°C. Do not aliquot the antibody
Recommended dilutions: WB: 1:1,000
Optimal dilutions should be determined by the end user.
Specificity:The β-Catenin Rabbit Polyclonal antibody detects endogenous β-Catenin proteins.
Alternative Names: beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082
Form: Liquid
Reactivity:M, R
Molecular Weight:~92KD
Western blot analysis of 1) 3T3, 2)Rat Liver, with β-Catenin Rabbit pAb BE3304 diluted at 1:2,000.