Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Product Name:Histone H3(Phospho Thr11) Rabbit Polyclonal Antibody
Isotype: IgG
Storage Buffer :PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol
Storage instructions:-20°C. Do not aliquot the antibody
Recommended dilutions: WB: 1: 5,00-1,000
Optimal dilutions should be determined by the end user.
Specificity:The Histone H3(Phospho Thr11) Rabbit Polyclonal Antibody can detects endogenous Histone H3(Phospho Thr11) protein.
Alternative Names:H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody
Molecular Weight:~15-17KD
Form: Liquid
Reactivity:H, R, M
Western blot analysis of extracts from Hela cells, untreated (-) or treated with Nocodazole (1μg/ml, 24 hr; +), using Phospho-Histone H3 (Thr11) Rabbit pAb (upper) BE3216 1:1000 and Histone H3 (2G2) Mouse mAb (lower) 1:2000.