Synthesized peptide derived from human Keratin 20.
内容
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
纯化方式
Immunogen affinity purified
浓度
500 ug/ml
产品形态
Liquid
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. This gene encodes a member of the keratin protein family and is found within a cluster of cytokeratin genes on chromosome 11. Keratins are cytoskeletal proteins that are preferentially expressed in epithelial cells. The encoded protein may help maintain intermediate filament organization in intestinal epithelium. Phosphorylation of this protein may also influence mucin secretion in the small intestine.
研究类别
1. Calnek, D., Quaroni, A. Differential localization by in situ hybridization of distinct keratin mRNA species during intestinal epithelial cell development and differentiation. Differentiation 53: 95-104, 1993.2. Moll, R., Schiller, D. L., Franke, W. W. Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J. Cell Biol. 111: 567-580, 1990.3. Rogers, M. A., Langbein, L., Winter, H., Ehmann, C., Praetzel, S., Korn, B., Schweizer, J. Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21. J. Biol. Chem. 276: 19440-19451, 2001.
[list_product_images]A02828 1 IHC P test on Mouse Stomach:
Formalin-fixed and paraffin embedded mouse stomach labeled Anti-CK20 Polyclonal Antibody at 1:200, followed by conjugation to the secondary antibody and DAB staining|A02828 1 IHC P test on Rat Cells:
Formalin-fixed and paraffin embedded rat tongue labeled with Rabbit Anti-CK20 Polyclonal Antibody at 1:200 followed by conjugation to the secondary antibody and DAB staining|A02828 1 WB test on Human Colon:
L1 human colon carcinoma lysates L2 rat brain lysates probed with Anti CK20 Polyclonal Antibody at 1:200 overnight at 4℃. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37℃. Predicted band 46kD. Observed band size:46kD.
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