A synthetic peptide corresponding to a sequence at the C-terminus of human NAT1 (172-201aa NEEFLHSDLLEDSKYRKIYSFTLKPRTIED), different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
内容
500 ug/ml antibody with PBS ,0.02% NaN3 , 1 mg BSA and 50% glycerol.
纯化方式
Immunogen affinity purified.
浓度
500 ug/ml
产品形态
Liquid
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
N-acetyltransferase 1 (arylamine N-acetyltransferase) is a protein that in humans is encoded by the NAT1 gene. This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
研究类别
1. "Entrez Gene: N-acetyltransferase 1 (arylamine N-acetyltransferase)".2. De León, J. H.; Vatsis, K. P.; Weber, W. W. (2000). "Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1". Molecular Pharmacology. 58 (2): 288–299.3. Gubin, A. N.; Njoroge, J. M.; Bouffard, G. G.; Miller, J. L. (1999). "Gene Expression in Proliferating Human Erythroid Cells". Genomics. 59(2): 168–177.
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). *Blocking peptide 可以联系我们购买。
[list_product_images]Figure 1. Western blot analysis of NAT1 using anti-NAT1 antibody (A01386-1). lane 1: A431 whole cell lysates. anti-NAT1 antigen affinity purified polyclonal antibody (Catalog # A01386-1)probed with a goat anti-rabbit IgG-HRP secondary antibody The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) . A specific band was detected for NAT1 at approximately 34KD. The expected band size for NAT1 is at 34KD.[/list_product_images]