For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -2426℃ for several months.
英文名:
Revaprazan HCl
库存:
详询
供应商:
详询
CAS号:
178307-42-1
规格:
2mg/5mg/10mg/50mg/1ml/10mM
规格:
2mg
产品价格:
¥485.0
规格:
5mg
产品价格:
¥723.0
规格:
10mg
产品价格:
¥923.0
规格:
50mg
产品价格:
¥3541.0
规格:
1ml/10mM
产品价格:
¥815.0
ID:T2405
PURITY:97%+
Formula:C22H24ClFN4
MolWt:398.9
Appearance:白色粉末
Solubility:G410 mM in DMSO
Bioactivity:Revaprazan Hydrochloride is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Revaprazan concentrates highly in the gastric parietal cell canaliculus and on entering this acidic environment is instantly protonated and binds competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.