For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -240℃ for several months.
英文名:
Losartan potassium
库存:
详询
供应商:
详询
CAS号:
124750-99-8
规格:
2mg/10mg/50mg/100mg/1ml/10mM
规格:
2mg
产品价格:
¥108.0
规格:
10mg
产品价格:
¥248.0
规格:
50mg
产品价格:
¥638.5
规格:
100mg
产品价格:
¥1088.0
规格:
1ml/10mM
产品价格:
¥218.0
ID:T0215
PURITY:0.99
Formula:C22H23ClN6O
MolWt:462.01
Appearance:白色晶体
Solubility:G4Soluble in DMSO
Bioactivity:Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.