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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant fragment corresponding to a region within amino acids 151 and 438 of Hemopexin.
- 形态:
liquid
- 保存条件:
Store at -20˚C
- 克隆性:
Polyclonal
- 适应物种:
Human
- 保质期:
12 months
- 抗原来源:
Rabbit
- 供应商:
南京赛戈巍生物科技有限公司
- 宿主:
Rabbit
- 应用范围:
WB
- 靶点:
Uniprot:P02790
- 抗体英文名:
Hemopexin Antibody
- 规格:
50ul/100ul
配方:Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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文献和实验血红素结合蛋白(hemopexin,Hpx)分子量5.7万,单链多肽,含糖量约22%。正常血浆中含量为500-1000μg/L,和游离血红素有特异结合能力。它可配合结合珠蛋白对血红蛋白进行处理。当广泛溶血时,血浆结合珠蛋白耗竭,循环中游离的血红蛋白可降解为珠蛋白和血红素两部分。血红素不溶于水,可与Hpx结合成复合物而运输到肝,分子中的铁可被机体重新利用,卟啉环降解为胆红素而由胆管排出。Hpx并不能与血红蛋白结合,仅可与血红素可逆地结合,而在血循环中反复利用,这是机体有效地保
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
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