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文献和实验Electrotransformation of Chinese Hamster Ovary Cells
Chinese hamster ovary (CHO) cells possess many advantages that make them among the most widely used and highly characterized mammalian cell lines. They are easy to culture, they grow rapidly without density dependence
Biallelic Gene Knockouts in Chinese Hamster Ovary Cells
Chinese hamster ovary (CHO) cells are the most common host cells and are widely used in the manufacture of approved recombinant therapeutics. They represent a major new class of universal hosts in biopharmaceutical production
Generation of High-Recombinant-Protein-Producing Chinese Hamster Ovary (CHO) Cells
The purpose of this chapter is to propose a practical procedure for the generation and selection of Chinese hamster ovary cells producing high levels of recombinant protein by combining in vitro and in vivo amplification of the foreign gene
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