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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 抗体名:
IL4 antibody抗体
- 抗体英文名:
IL4 antibody
- 靶点:
IL4
- 浓度:
- 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml
- 应用范围:
IHC-P, WB
- 宿主:
Rabbit
- 适应物种:
Human, Mouse, Rat
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb360766
- 级别:
科研级
- 库存:
88
- 供应商:
biorbyt
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 形态:
10 mM PBS, 0.02% sodium azide
- 亚型:
IgG
- 免疫原:
KLH conjugated synthetic peptide derived from human IL4. Please contact us for the exact immunogen sequence. The peptide is available as orb374976.
- 规格:
100 ug
别名:IL4
免疫原:KLH conjugated synthetic peptide derived from human IL4. Please contact us for the exact 免疫原 sequence. The peptide is available as orb374976.
分子量:17 kDa
应用稀释比例:IHC-P: 1:100-500, WB: 1:100-2000
纯度:Polyclonal antibodies are purified by peptide affinity chromatography
保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NCBI:000409, 000418
Entrez:3566
UniProt ID:P20096, P05112, P07750
Note:For research use only.



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- 作者
- 内容
- 询问日期
文献和实验cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production
磷酸化后可传递激活信号。此处参与的JakPTK家族成员为Jak2和Tyk2,活化转录因子STAT4,后者以二聚体形式进入细胞核,激活IFNG基因并抑制IL-4基因激活,最终完成Thl的分化。 如果IL4出现,β2亚单位表达受阻,剩下的β1不足以和IL-12结合而不能启动上述信号转导通路,而转为由IL-4借助相应的受体IL4R,在TCR信号的参与下,启动另一条由Jakl/Jak3-STAT 6参与的通路,首先激活Th2亚群专一性转录因子GATA-3,后者不仅参与激活IL4基因,并阻抑
1, CALM2, CALM3, CAMK2B, CAMK4, CNR1, ITK, MAP2K7, NCK2, PAK1, PPIA, PPP3CB, PPP3CC, PPP3R1, TRPV6, VAV1, VAV2, VAV3. Ligands: CCL2, CSF2, CSF3, IFNA1, IFNB1, IFNG, IL1A, IL1B, IL2, IL3, IL4, IL6, IL8, IL10, IL12A, IL12B, IL13, IRF1, LTA, TGFB1, TNF
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