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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
- 保质期:
6个月
- 英文名:
Rabbit PD-1 Protein, Fc Tag
- 库存:
详询客服
- 供应商:
biorbyt
- 规格:
100 ug
应用笔记:This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.6 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
反应种属:Rabbit
纯度:95%
分子量:42.6 kDa
表达区域:Leu 25 - Gln 167
内毒素:1.0 EU per μg
标签:C-Fc
防腐剂:Tris with Glycine, Arginine and NaCl, pH 7.5
形态:Powder
标记物:Unconjugated
Uniprot ID:G1SUF0
Note:For research use only.

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文献和实验Mapping Protein Distributions on Polytene Chromosomes by Immunostaining
serum, obtained from the same species as the secondary antibody. Depending on the method employed, use anti-rabbit IgG (Fc) horseradish peroxidase (HRP) conjugate (1:100 dilution), a biotin-conjugated secondary antibody, or a fluorescence-conjugated
ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
Protein A, derived from the cell wall of Staphylococcus aureus , and protein G, derived from the cell wall of certain strains of b -hemolytic Streptococcci , binds the Fc region
来瓶「红牛」继续干!唐力团队发现 IL-10 可激活终末耗竭 T 细胞,为增强肿瘤免疫治疗提供新思路
性。作者将 PMEL 和 OT-I(T 细胞受体转基因 T 细胞,可识别卵清蛋白 OVA 抗原)CD8+ T 细胞一起过继转移给 B16F10 肿瘤小鼠,结果发现 IL-10–Fc 显著增加了 PMEL 的 PD-1+TIM-3 + 双阳性细胞和 PMEL 总细胞的比例,但不影响 OT-I T 细胞。 图片来源:Nature Immunology作者发现剔除耗竭祖 T 细胞后,IL-10–Fc 对终末耗竭性 T 细胞的作用并没有受到影响,提示 IL-10–Fc 对终末耗竭性 CD8+ TILs 的扩增
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