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文献和实验Aptamers are single-stranded nucleic acids or peptides that can bind target molecules with high affinity and specificity. The conformation of an aptamer usually changes upon binding to its target analyte, and this property has been used
Roche 454(GS FLX Titanium System)超高通量测序技术原理
2005年底,454公司推出了革命性的基于焦磷酸测序法的超高通量基因组测序系统——Genome Sequencer 20 System,被《Nature》杂志以里程碑事件报道,开创了边合成边测序的先河。2007年又推出了性能更优的第二代基因组测序系统——Genome Sequencer FLX System。2008年10月,454推出了全新的GS FLX Titanium系列试剂和软件,让GS FLX的通量一下子提高了5倍,准确性和读长
Catalytic M1GS RNA as an Antiviral Agent in Animals
The use of RNase P ribozyme (M1GS catalytic RNA) for inhibition of murine cytomegalovirus (MCMV) propagation in mice is described in this chapter. General information about RNase P based technology is included and followed by detailed
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