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文献和实验Probing the Mechanics of the Complete DNA Transcription Cycle in Real-Time Using Optical Tweezers
here, which allows the complete transcription cycle (i.e., promoter binding, initiation, elongation and termination) to be followed in real-time using dual-trap optical tweezers and a unique “three-bead” geometry. This single-molecule transcription assay can be used
In Silico and Wet-Bench Identification of Nuclear Matrix Attachment Regions
or multigenic families, each constituting a single chromatin domain. With the sequencing phase of various genome projects complete, in silico tools are being developed to identify the long-range control elements that modulate gene expression. This information
Optical Properties of Neural Tissue
The optical properties of neural tissues play critical roles in all types of optical imaging methods. The wavelength-dependent absorption and scattering properties of tissue influence imaging resolution, penetration depth, and often provide
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