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文献和实验fixation, 2) immunoprecipitation of specific chromatin fragments using antibody against the protein of interest and 3) analysis of immunoprecipitated fractions to determine if target DNA is bound by the protein of interest (evidenced by enrichment of DNA
Applicator and Electrode Design for In Vivo DNA Delivery by Electroporation
the DNA to the target tissue and the subsequent step of electroporation. This chapter presents the electrical and biological principles underlying applicator and electrode design, gives an overview of existing devices, and discusses their advantages
c-kit Mutational Analysis in Paraffin Material
-oncogene in extracutaneous organs. The receptor molecule KIT is a potential therapeutic target for tyrosine kinase inhibitors. KIT mutations have been described in more than 80% of SM, but only in the minority of cutaneous mastocytoses (CM). Usually exon 17
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