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文献和实验Clonality - X Chromosome Inactivation Assay
can utilize X chromosome inactivation (methylation) to determine the clonality status of a tumor or premalignant lesion in females. The technique is based on a methylation-sensitive restriction enzyme and analysis of a polymorphic locus on the X chromosome
T1.1 =26.2 T1.2 =43-26.2=16.8 T2.1 =53-26.2=26.8 T2.2 =44-26.2=17.2 3.计算x2 值 按公式20.12代入 4.查x2 值表求P值 在查表之前应知本题自由度。按x2 检验的自由度v=(行数-1)(列数-1),则该题的自由度v=(2-1)(2-1)=1,查x2 界值表(附表20-1),找到x2 0.001
Clonality - X Chromosome Inactivation Assay
Clonality - X Chromosome Inactivation Assay This method was successful in our lab using prostate tissue and for our specific objectives. Investigators must be aware that they will need to tailor the following protocol for their own research
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