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文献和实验can be characterized by their fatty acids that differ in chain length, degree of unsaturation, configuration, and position of the double bonds, and the presence of other functionalities (see Note 1 ). High-performance liquid chromatography (HPLC) methods
LC-MS Metabonomics Methodology in Biomarker Discovery
chemistry. The main advantages of liquid chromatography–mass spectrometry (LC-MS) technique include high sensitivity, high resolution, and wide dynamic range. LC-MS–based technology platforms combined with multivariate statistical methods are used to explore
HPLC/MS/MS-Based Approaches for Detection and Quantification of Eicosanoids
, including asthma, chronic obstructive pulmonary disease (COPD), cardiovascular disease, and cancer. Because the endogenous levels of eicosanoids are quite low, sensitive and specific analytical methods are required to reliably quantify these compounds. High
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