Imatinib Mesylate inhibits c-kit, PDGFR and c-ABL by perfectly binding to adenosine triphosphate (ATP)-binding sites of the c-kit protooncogene product, platelet-derived growth factor receptor (PDGFR), and abelson kinase (c-ABL).http://www.creative-enzymes.com/product/Imatinib-Mesylate_2228.html