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详见说明
Tylosin
充足
杭州昊鑫生物
1401-69-0
50mg
生物活性 | Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3]. |
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IC50 & Target |
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体外研究 (In Vitro) |
Tylosin exerts antibacterial effects by binding to 23S rRNA of the bacterial ribosomal 50S subunit [1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Tylosin (10-500 mg/kg; s.c.) generally suppresses the elevated TNF-α and IL-1β levels and increases the IL-10 levels in the Lipopolysaccharide (LPS) -treated animals[4]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 | 916.10 |
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Formula | C46H77NO17 |
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CAS 号 | |||||||||||||||||
中文名称 | 泰乐菌素;泰洛星;泰乐霉素 |
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结构分类 | |||||||||||||||||
来源 | Streptomyces fradiae |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 100 mg/mL (109.16 mM) H2O : 0.67 mg/mL (0.73 mM; Need ultrasonic) * "≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百 |
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