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详见说明
Spectinomycin dihydrochloride
充足
杭州昊鑫生物
21736-83-4
1g
生物活性 | Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the Bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM[1]-[5]. |
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IC50 & Target | bacterial ribosomal subunit[5] |
体外研究 (In Vitro) |
Spectinomycin dihydrochloride selectively inhibits protein synthesis in cells and in extracts of Escherichia coli: MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Spectinomycin dihydrochloride (20 mg/kg; i.m.; 20-100 mg/kg; 9 d) shows the safety in healthy chicks[4].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 | 405.27 |
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Formula | C14H26Cl2N2O7 |
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CAS 号 | |||||||||||||||||
中文名称 | 盐酸奇霉素;盐酸壮观霉素 |
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结构分类 | |||||||||||||||||
来源 | bacterium Streptomyces spectabilis |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
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储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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溶解性数据 | In Vitro: H2O : ≥ 100 mg/mL (246.75 mM) * "≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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