手机验证
4°C
详见说明
Pramipexole
充足
杭州昊鑫生物
104632-26-0
500mg
生物活性 | Pramipexole is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS)[1][2][3]. |
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体外研究 (In Vitro) |
Pramipexole shows a low binding affinity for D1-type receptor, with an IC50 of >50,000 nM[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Pramipexole (0.25-1 mg/kg; i.p.) significantly reduces the infarction volume in animals[5]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 | 211.33 |
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Formula | C10H17N3S |
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CAS 号 | |||||||||||||||||
中文名称 | 普拉克索;米拉帕 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 | In Vitro: DMSO : 100 mg/mL (473.19 mM; Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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