IL-17A Antibody-APC；流式抗体；Clone

产品名称 ：IL-17A Antibody-APC；流式抗体；Clone number：17F3
克隆类型 ：Mouse Monoclonal Antibody；Clone number：17F3
货 号 ：HT1610485
规 格 ：25/100 μg ;
亚 型 ：
Mouse IgG1
浓 度 ：
Concentration：0.2 mg/ml
缓 冲 液 ：
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
产品描述 ：
IL-17A is a cystine-linked homodimeric pro-inflammatory cytokine produced by TH17 cells,a distinct CD4+ T cell lineage. IL-17A stimulates the production of the pro-inflammatory cytokines IL-1β, TNFα, and IL-6. IL-17A also induces production of the neutrophil chemoattractants IL-8, CXCL1, and CXCL6 thereby bridging adaptive and innate immunity . IL-17A is intimately involved in mucosal immunity against bacterial infections and has a putative role in some autoimmune disorders . IL-17A effects appear to be exerted primarily through binding to the IL-17RA.IL-17A binding induces production of cytokines, chemokines and other proteins through activation of the ERK1/2 MAP kinase, PI3K/Akt, p38, and NF-κB pathways . Phosphorylation of some Jaks and Stats has been observed.
适用物种 ：
Mouse
应用范围 ：
FC
应用说明 ：
The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl
保存条件 ：
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
标 记 物 ：
APC（其他荧光标记请咨询我们）