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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD45R (B220)
- 亚型:
Rat IgG2a
- 形态:
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
- 保存条件:
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
- 克隆性:
Monoclonal Antibody
- 标记物:
FITC
- 适应物种:
Mouse
- 宿主:
Rat
- 应用范围:
FC
- 浓度:
Concentration:0.2 mg/ml
- 靶点:
Clone number:RA3-6B2
- 抗体英文名:
CD45R (B220) Antibody-FITC;流式抗体
- 抗体名:
CD45R (B220) Antibody-FITC;流式抗体
- 规格:
50/500 μg
克隆类型 :Rat Monoclonal Antibody;Clone number:RA3-6B2
货 号 :HT1610231
规 格 :50/500 μg ;
亚 型 :
Rat IgG2a
浓 度 :
Concentration:0.2 mg/ml
缓 冲 液 :
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
产品描述 :
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. 应用范围:FCM
适用物种 :
Mouse
应用范围 :
FC
应用说明 :
The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl
保存条件 :
Store at 4°C and protected from prolonged exposure to light. Do not freeze.
标 记 物 :
FITC(其他荧光标记请咨询我们)
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文献和实验附表1),但还有一些重要的Ly抗原尚无相应的CD编号,如Ly- 6A、- 6C、- 6D、- 6E、- 6G,Ly- 49- A、- C、- D、- E、- I,Ly- 51,Ly- 76和Ly- 77等。(三) 某些人和小鼠CD 分子编号相同,但功能有所差别1. B细胞 CD45R/B220(相应mAb为RA3- 6B2)是小鼠全B细胞最常用标记,也表达于活化T细胞、活化NK细胞和NK祖细胞。CD19是B细胞较特异的标记。2. T细胞 小鼠重要的T细胞标记有Thy- 1(CD90)和成熟T
MATERIALS T-cell: CD2 IgG2b, 01171D B-cell: B220 (CD45R) IgG2a, 01121A CD3 IgG2b, 28001D Monocytic: Mac1 (CD11b) IgG2b, 01711A CD5 IgG2a, 01031
Intracellular Cytokine Staining Protocol
CD45R/B220 RA3-6B2 14-0452 also on NK progenitors, LAK, activated T Natural Killer Cells (NK) CD49b/DX5 DX5 14-5971
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