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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Bcl-2-modifying factor (BMF)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human Bcl-2-modifying factor (BMF)品名简称:
Recombinant Human BMF protein货号:
CSB-EP850383HU规格:
20μg价格:
1344LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
BMFUniprot No.:
Q96LC9别名:
Bcl 2 modifying factor; Bcl-2-modifying factor; Bcl2 modifying factor; Bmf; BMF_HUMAN; FLJ00065种属:
Homo sapiens (Human)蛋白长度:
Full Length of BC069505来源:
E.coli分子量:
47.5 kDa表达区域:
1-184aa氨基酸序列:
MEPSQCVEELEDDVFQPEDGEPVTQPGSLLSADLFAQSLLDCPLSRLQLFPLTHCCGPGLRPTSQEDKATQTLSPASPSPGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAVLPIGEQPPEGQWQHQAEVQIARKLQCIADQFHRLHVQQHQQNQNRVWWQILLFLHNLALNGEENRNGAGPR蛋白标签:
N-terminal GST-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
13-23 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
May play a role in apoptosis. Isoform 1 seems to be the main initiator.功能2:
May play a role in apoptosis. Isoform 1 seems to be the main initiator.文献:
"Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." Puthalakath H., Villunger A., O'Reilly L.A., Beaumont J.G., Coultas L., Cheney R.E., Huang D.C.S., Strasser A. Science 293:1829-1832(2001)研究领域:
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文献和实验ChIP on Chip Assays: Genome-Wide Analysis of Transcription Factor Binding and Histone Modifications
factors and chromatin-modifying proteins. Chromatin immunoprecipitation assay is a well-established tool for investigating the interactions between regulatory proteins and DNA at distinct stages of gene activation. ChIP coupled with DNA microarrays, known
可以与Bcl-2家族在线粒外膜结合而使之灭活,从而促进凋亡的发生。反之,生存因子(survival factor,IL-3)可以使Bad磷酸化而存在于胞质中。Bim主要与细胞内的微管形成复合体,在凋亡早期与微管分离而进入线粒体,具体机制尚不清楚。有研究发现Bim缺乏的小鼠,其免疫系统对凋亡诱导因素不敏感。此外,BH3-only家族的另一个成员Noxa被发现与p53引导的凋亡调控有关。新近发现另一个基因PUMA(p53 upregulatedmodulatoro{apoptosis)编码两个包含BH
Modification of Materials With Bioactive Peptides
desired in applications such as tissue engineering and regenerative medicine. For example, transforming growth factor-beta (TGF-β) has been immobilized to polymeric scaffold materials to increase the synthesis of extracellular matrix (ECM) proteins
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