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Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
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货期：1-2天
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MedChemExpress LLC
- CAS号：
1070773-09-9
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10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥660.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥600.0 |
| 规格： | 10 mg | 产品价格： | ￥900.0 |
| 规格： | 25 mg | 产品价格： | ￥1800.0 |
| 规格： | 50 mg | 产品价格： | ￥2800.0 |
| 规格： | 100 mg | 产品价格： | ￥4500.0 |
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RK-33
CAS No. : 1070773-09-9
MCE 国际站：RK-33
产品活性：RK-33 是 RNA helicase 的抑制剂，可抑制 DDX3 的活性。
研究领域：Others
作用靶点：Others
In Vitro: RK-33 shows inhibition of many kinds of cancer cells with IC50 of 3-6 µM, while PC3 is much less sensitive to RK-33 (IC50 >12 µM). RK-33 treatment causes a significant accumulation in the G1 phase for DU145 and LNCaP, although treatment with RK-33 causes only a moderate accumulation of the G1 phase for 22Rv1, and the treated cells have significantly reduced G2 phase. RK-33 treatment also causes 12 moderate G1 accumulation in 22Rv1. RK-33-loaded NPs demonstrate cytotoxicity to MCF-7 cells in a dose-dependent manner, while equivalent doses of empty NPs have no killing effect. The IC50 value of 5% RK-33 loaded NPs is 49 μg/mL, and the IC50 value of 10% RK-33 loaded NPs is 25 μg/mL.
In Vivo: There is more cell death (pyknotic or condensed nuclei) admixed with fibrin and interstitial edema in the tumors from mice from the combination RK-33 and radiation group compared to the control or single treatment groups. The treatment combination of RK-33 and radiation has an advantage in reducing tumor proliferation. In the mice treated with RK-33-PLGA, RK-33 can be detected in the plasma (34 μg/mL) and liver (28 μg/g), but not lungs.
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文献和实验xhxhk 染色体 2q33 什么意思？是第几条的什么位点？ zhujoker 2号染色体长臂33区 glliutjmu 2号染色体长臂3区3带 中间没有.,呵呵。 本文由丁香园论坛提供，想了解更多有用的、有意思的前沿资讯以及酷炫的实验方法的你，都可以成为师兄的好伙伴 师兄微信号：shixiongcoming
dongreyuan 有的抗体名称上面写着Ab-33，比如，β-catenin（Ab-33）antibody，请问，Ab-33是什么意思？ bettyzyj 这个抗体是非磷酸化的抗体non-phospho-antibody ，33 代表的是基因位点 dongreyuan 谢谢了 yhwangcams bettyzyj wrote
LLC-RK1 Cell Screening Test for Nephrotoxicity
In this test, kidney-derived cells are cultured in the presence of test compounds whose cytotoxicity is then determined by the Neutral Red method, and serves as an indicator of potential nephrotoxicity (1 ). Healthy LLC-RK1 cells
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