组织金属蛋白酶抑制因子1(TIMP1)重组蛋白

组织金属蛋白酶抑制因子1(TIMP1)重组蛋白

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  • ¥2340
  • cloud-clone corp(优尔)
  • 武汉
  • RPA552Eq01
  • 2025年07月11日
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    • 详细信息
    • 技术资料
    • 保存条件

      详见说明

    • 保质期

      详见说明

    • 英文名

      Recombinant Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)

    • 库存

      充足

    • 供应商

      杭州昊鑫生物

    • 规格

      50ug

    组织金属蛋白酶抑制因子1(TIMP1)重组蛋白

    组织金属蛋白酶抑制因子1(TIMP1)重组蛋白
    Purity≥ 95%;Fragment:Cys24~Ser178; Predicted Molecular Mass(KD):47.3kDa

    优尔生的一级代理:杭州昊鑫生物

    优尔生位于武汉出口加工区,已整体通过ISO 9001:2008、ISO 13485:2003质量管理体系认证,以提供生命科学科研用检测试剂为主,75%以上的服务对象位于欧美国家。凭借着深厚的技术积累和庞大的引物、cDNA、质粒、杂交瘤细胞“种子库”和检测试剂半成品库库存,能够做到约11,000种蛋白、19,000种抗体以及71558种检测试剂盒立等可取。蛋白项目部拥有四大技术平台,包括多肽合成平台、小分子抗原性改造平台、天然蛋白提取平台和采用原核(E.Coli)表达系统与真母、杆状病毒-昆虫细胞、哺乳动物细胞)表达系统的重组蛋白表达平台。抗体项目部拥有完备的单克隆抗体和多克隆抗体制备平台。免疫应用部负责检测试剂盒的研制,主要是ELISA和CLIA试剂盒。成品检测部负责所有蛋白、抗体以及检测试剂盒产成品的检测及质量控制。公司实行三级质量控制,包括原料检测、半成品检测及成品检测。
    • 编号RPA552Eq01
    • 物种Equus caballus; Equine (Horse,马) 相同的名称,不同的物种。
    • 来源原核表达
    • 宿主E.coli
    • 内毒素水平<1.0EU/µg(LAL法测定)
    • 亚细胞定位n/a
    • 预测分子量47.3kDa
    • 实际分子量47.3kDa(差异分析请参阅说明书)
    • 片段与标签Cys24~Ser178 with N-terminal His and GST Tag
    • 缓冲液成份磷酸盐缓冲液(pH7.4,含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.)
    • 性状冻干粉
    • 纯度> 95%
    • 等电点-
    • 应用Positive Control; Immunogen; SDS-PAGE; WB.
      如果需要有生物活性的蛋白,请参见活性蛋白。
    • 下载英文说明书 中文说明书
    • 规格10µg50µg 200µg 1mg 5mg

    产品包装图模拟
    组织金属蛋白酶抑制因子1(TIMP1)重组蛋白 组织金属蛋白酶抑制因子1(TIMP1)重组蛋白

    用法

    PBS或其它。

    储存

    避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。

    稳定性

    热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

    参考文献

    杂志 参考文献
    Experimental & Translational Stroke Medicine Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke [PubMed: 21679435]
    PLoS ONE A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches [Plosone: Source]
    Polski Przeglad Chirurgiczny Concentration of gelatinases and their tissue inhibitors in pancreatic inflammatory and neoplastic tumors and their influence on the early postoperative course [Pubmed: 23585206]
    Thromb Haemost. Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke [Pubmed:24671655]
    The Scientific World Journal Pass-predicted hepatoprotective activity of Caesalpinia sappan in thioacetamide-induced liver fibrosis in rats [Pubmed:24701154]
    PLOS ONE The Complementary Effects of Atorvastatin and Exercise Treatment on the Composition and Stability of the Atherosclerotic Plaques in ApoE Knockout Mice [Pubmed:25264981]
    Mediators of Inflammation Metalloproteinases and Their Tissue Inhibitors in Comparison between Different Chronic Pneumopathies in the Horse [Journals: Mi]
    PLOS Adiponectin Attenuates Lung Fibroblasts Activation and Pulmonary Fibrosis Induced by Paraquat [PubMed: 25945502]
    Canadian Journal of Physiology and Pharmacology Modified Citrus Pectin stops progression of liver fibrosis by inhibiting galactin-3 and inducing apoptosis of stellate cells [Doi: Abs]
    PLoS One Silencing of Paternally Expressed Gene 10 Inhibits Trophoblast Proliferation and Invasion [PubMed: 26680220]
    Kyselov Влияние диуретиков с антиальдостероновым действием на состояние межклеточного матрикса и раннее постинфарктное ремоделирование левого … [Article: View]
    Оригинальные исследования / Original researches матриксу та ранн [Article: Viewfile]
    Basic Research CTGF upreCavia (Guinea pig )lation correlates with MMP-9 level in airway remodeling in a murine model of asthma [Journal:27699]
    J Orthop Res. Tetrandrine suppresses articular inflammatory response by inhibiting pro-inflammatory factors via NF-κB inactivation. [Pubmed:26748661]
    Int Wound J. From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases. [Pubmed:26991748]
    Am J Pathol. Serum Osteopontin as a Novel Biomarker for Muscle Regeneration in Duchenne Muscular Dystrophy. [Pubmed:26963343]
    Journal of Orthopaedic Research Tetrandrine suppresses articular inflammatory response by inhibiting pro‐inflammatory factors via NF‐κB inactivation [pubmed:26748661]
    Canadian Journal of Veterinary Research Evaluation of hyaluronic acid, procollagen type III N-terminal peptide, and tissue inhibitor of matrix metalloproteinase-1 as serum markers of canine hepatic fibrosis [pubmed:27733785]
    BMC Veterinary Research Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy incombination with environmental dust reduction in equine recurrent airway obstruction. [pubmed:27938355]
    Journal of Cellular Physiology Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Models [pubmed:27739057]
    Toxicology and Applied Pharmacology Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) [pubmed:28974454]
    Journal of Applied Animal Research Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts:an in vitro approach to bovine digital dermatitis [10.108:09712119.2017.1335208]
    Cellular Physiology and Biochemistry The MiR-495/Annexin A3/P53 Axis Inhibits the Invasion and EMT of Colorectal Cancer Cells [pubmed:29224019]
    International Wound Journal From varices to venous ulceration: the story of chronic venous disease described by metalloproteinases [pubmed:26991748]
    Archives of Medical Science CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma. [pubmed:28507585]
    APMIS Hepatoprotectivity of Panduratin A against liver damage: demonstration with a rat model of cirrhosis induced by thioacetamide [Pubmed:30058214]
    Journal of Applied Animal Research Hypoxia enhances secretion of matrix metalloproteinases in bovine dermal fibroblasts: an approach to bovine digital dermatitis [10.1080:09712119.2017.1335208]
    МАТРИКСНЫЕ МЕТАЛЛОПРОТЕИНАЗЫ: ЗНАЧЕНИЕ В РЕМОДЕЛИРОВАНИИ СЕРДЦА У ПАЦИЕНТОВ С ДИСПЛАЗИЕЙ СОЕДИНИТЕЛЬНОЙ ТКАНИ []
    Mediators of Inflammation Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma []
    International Journal of Clinical and Experimental Medicine Expression of MMP-9 and TIMP-1 in rat models of pressure ulcer and their significance []
    Oncology Research MicroRNA-6884-5p regulates the proliferation, invasion and EMT of gastric cancer cells by directly targeting S100A16 [Pubmed: 31796150]
    Open Medicine Plasma matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 as prognostic biomarkers in critically ill patients [Pubmed: 32190734]
    Scientific Reports Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis [Pubmed: 31980722]
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS Extracellular matrix collagen biomarkers levels in patients with chronic thromboembolic pulmonary hypertension [Pubmed: 33175289]
    Molecular Medicine Reports MicroRNA-1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post-transcriptional suppression of Ihh expression [Pubmed: 32705199]
    International Journal of Environmental Research and Public Health Biomarkers Facilitate the Assessment of Prognosis in Critically Ill Patients with Primary Brain Injury: A Cohort Study [Pubmed: 32575870]
    . Почечная дисфункция при преэклампсии: прогнозирование и дифференциальный диагноз. Часть 1 []
    MEDIATORS OF INFLAMMATION MMP-9 Concentration in Peritoneal Fluid Is a Valuable Biomarker Associated with Endotoxemia in Equine Colic [33488296]
    CLINICAL SCIENCE Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes [33491733]
    DOCSBAY Intermittent Pacing Therapy Favorably Modulates Infarct Remodeling [28386775]
    EVALUATION OF DYNAMICS OF METALLOPROTEINASE ACTIVITY AND INDICATORS OF OXIDATIVE STRESS IN THE TREATMENT OF BURNS WITH A NEW DERIVATIVE OF N-ACETYL-6- AMINOHEXANOIC ACID []
    VETERINARY OPHTHALMOLOGY Concentrations of tissue inhibitor of matrix metalloproteinase‐1 and hyaluronic acid in canine amniotic membranes cryopreserved for different time points and its … [34240563]
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