表面活性物质关联蛋白D(SPD)重组蛋白

表面活性物质关联蛋白D(SPD)重组蛋白

Purity≥ 92%；Fragment：Ala21~Phe375； Predicted Molecular Mass(KD)：37.0kDa

优尔生的一级代理：杭州昊鑫生物

优尔生位于武汉出口加工区，已整体通过ISO 9001:2008、ISO 13485:2003质量管理体系认证，以提供生命科学科研用检测试剂为主，75%以上的服务对象位于欧美国家。凭借着深厚的技术积累和庞大的引物、cDNA、质粒、杂交瘤细胞“种子库”和检测试剂半成品库库存，能够做到约11,000种蛋白、19,000种抗体以及72605种检测试剂盒立等可取。蛋白项目部拥有四大技术平台，包括多肽合成平台、小分子抗原性改造平台、天然蛋白提取平台和采用原核（E.Coli）表达系统与真母、杆状病毒-昆虫细胞、哺乳动物细胞）表达系统的重组蛋白表达平台。抗体项目部拥有完备的单克隆抗体和多克隆抗体制备平台。免疫应用部负责检测试剂盒的研制，主要是ELISA和CLIA试剂盒。成品检测部负责所有蛋白、抗体以及检测试剂盒产成品的检测及质量控制。公司实行三级质量控制，包括原料检测、半成品检测及成品检测。

• 编号RPB039Hu01
• 物种Homo sapiens (Human，人) 相同的名称，不同的物种。
• 来源原核表达
• 宿主E.coli
• 内毒素水平<1.0EU/µg(LAL法测定)
• 亚细胞定位分泌, 细胞外基质
• 预测分子量36.8kDa
• 实际分子量43kDa(差异分析请参阅说明书)
• 片段与标签Ala21~Phe375 with N-terminal His Tag
• 缓冲液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• 性状冻干粉
• 纯度> 90%
• 等电点6.3
• 应用Positive Control; Immunogen; SDS-PAGE; WB.
  如果需要有生物活性的蛋白，请参见活性蛋白。
• 下载英文说明书 中文说明书
• 规格10µg50µg 200µg 1mg 5mg

产品包装图模拟

序列

用法

Reconstitute in ddH₂O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

参考文献

杂志	参考文献
The American Journal of Rhinology & Allergy	Surfactant protein A and D in chronic rhinosinusitis with nasal polyposis and corticosteroid response [Ingenta: art00005]
J Occup Health	Evaluation of acute oxidative stress induced by NiO nanoparticles in vivo and in vitro [PubMed: 21233593]
Inhalation Toxicology	Comparison of acute oxidative stress on rat lung induced by nano and fine-scale, soluble and insoluble metal oxide particles: NiO and TiO2 [PubMed: 22642288]
American Journal of Rhinology & Allergy	Detection of surfactant proteins A, B, C, and D in human nasal mucosa and their regulation in chronic rhinosinusitis with polyps [PubMed: 23406594]
Plos one	Staphylococcus aureus and Pseudomonas aeruginosa Express and Secrete Human Surfactant Proteins [PubMed: PMC3551896]
Plos one	The Detection of Surfactant Proteins A, B, C and D in the Human Brain and Their Regulation in Cerebral Infarction, Autoimmune Conditions and Infections of the CNS [PubMed: PMC3787032]
	Nachweis und Charakterisierung des Oberfl?chenproteins PLUNC (Palate, Lung and Nasal Clone Protein) an der Augenoberfl?che und Bedeutung für das Trockene Auge [Opus4:Source]
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Frontiers in Aging Neuroscience	Correlations of Ventricular Enlargement with Rheologically Active SurfactantProteins in Cerebrospinal Fluid. [pubmed:28101052]
American Journal of Physiology. Lung Cellular and Molecular Physiology	Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency. [pubmed:29167126]
Molecular Neurobiology	Rheologically Essential Surfactant Proteins of the CSF Interacting with Periventricular White Matter Changes in Hydrocephalus Patients–Implications for CSF … [Doi: 10.1007/s12035-019-01648-z]
Respir Res	Elevated plasma levels of epithelial and endothelial cell markers in COVID-19 survivors with reduced lung diffusing capacity six months after hospital … [Pubmed:35189887]
Virology Journal	The association between sPD-1 levels versus liver biochemistry and viral markers in chronic hepatitis B patients: a comparative study of different sPD-1 … [Pubmed:35361235]