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- 详细信息
- 文献和实验
- 技术资料
- 库存:
3周左右
- 供应商:
研卉生物
- 检测范围:
62.3-4000 pg/mL
- 检测方法:
ELISA
- 适应物种:
Human
- 样本:
cell culture supernatant, serum, plasma (EDTA, citrate, heparin)
- 规格:
96T
货号BMS2210
Reactivity
| Human | |
| Analyte Parameters | GITR |
| Sample Volume | 50 µL |
| Suitable Sample Types | cell culture supernatant, serum, plasma (EDTA, citrate, heparin) |
| Sensitivity | 9.7 pg/mL |
| Standard Curve Range | 62.3-4000 pg/mL |
| Components | Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human GITR Biotin-Conjugate anti-human GITR monoclonal antibody Streptavidin-HRP Human GITR Standard lyophilized, 8000 pg/mL upon reconstitution Sample Diluent Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA) Wash Buffer Concentrate 20x (PBS with 1% Tween 20) Substrate Solution (tetramethyl-benzidine) Stop Solution (1M Phosphoric acid) Adhesive Films |
| Reported Applications | ELISA |
Glucocorticoid-induced TNFR-related protein (GITR) is a member of the tumor necrosis factor receptor (TNF-R) and is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18).
GITR is receptor for TNFSF18 and seems to interact with activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR plays role in activation of NF-kappa-B via the TRAF2/NIK pathway.
It has been shown that antibodies to GITR promote an anti-tumor response through loss of Treg lineage stability.
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文献和实验Warnings And Limitations This product is for research use only. Not intended for any animal or human therapeutic or diagnostic use unless otherwise stated. Follow appropriate laboratory guidelines. This product contains 0.02% sodium azide
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