200ug/ml antibody with PBS ,0.02% NaN3 , 1mg BSA and 50% glycerol.
纯化方式
Ascites
浓度
200ug/ml
产品形态
Liquid
保存条件
12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料
The microtubule-associated proteins(MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles(NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau(MTBT1) is mapped to chromosome 17q21.
研究类别
1. Andreadis, A.; Brown, W. M.; Kosik, K. S. : Structure and novel exons of the human tau gene. Biochemistry 31: 10626-10633, 1992. 2. Donlon, T. A.; Harris, P.; Neve, R. L. : Localization of microtubule-associated protein tau (MTBT1) to chromosome 17q21. (Abstract) Cytogenet. Cell Genet. 46: 607, 1987.
Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.