cytokine receptor class-II CRF2-4,cytokine receptor family II, member 4
Gene Summary:
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq
omim id:
,
Gene Description:
interleukin 10 receptor, beta
Gene Alias:
CDW210B,CRF2-4,CRFB4,D21S58,D21S66,IL-10R2
Gene Name:
IL10RB
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Supplied Product:
Antibody pair set content: 1. Antibody pair for IP: rabbit polyclonal anti-IL10RB (300 ul) 2. Antibody pair for WB: mouse polyclonal anti-IL10RB (50 ul)
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB) Immunoprecipitation of IL10RB transfected lysate using rabbit polyclonal anti-IL10RB and Protein A Magnetic Bead (), and immunoblotted with mouse polyclonal anti-IL10RB.
Reactivity:
Human
Product Description:
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.