The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
omim id:
,
Gene Description:
gelsolin (amyloidosis, Finnish type)
Gene Alias:
DKFZp313L0718
Gene Name:
GSN
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Supplied Product:
Antibody pair set content: 1. Antibody pair for IP: rabbit polyclonal anti-GSN (300 ul) 2. Antibody pair for WB: mouse purified polyclonal anti-GSN (50 ug)
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB) Immunoprecipitation of GSN transfected lysate using rabbit polyclonal anti-GSN and Protein A Magnetic Bead (), and immunoblotted with mouse purified polyclonal anti-GSN.
Reactivity:
Human
Product Description:
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.