DNase II alpha,DNase II, lysosomal,R31240_2,acid DNase
Gene Summary:
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq
Gene Description:
deoxyribonuclease II, lysosomal
Gene Alias:
DNASE2A,DNL,DNL2
Gene Name:
DNASE2
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Supplied Product:
Antibody pair set content: 1. Antibody pair for IP: rabbit polyclonal anti-DNASE2 (300 ul) 2. Antibody pair for WB: mouse purified polyclonal anti-DNASE2 (50 ug)
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB) Immunoprecipitation of DNASE2 transfected lysate using rabbit polyclonal anti-DNASE2 and Protein A Magnetic Bead (), and immunoblotted with mouse purified polyclonal anti-DNASE2.
Reactivity:
Human
Product Description:
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.