highly expressed in cancer, rich in leucine heptad repeats,kinetochore associated 2
Gene Summary:
HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.[supplied by OMIM
Gene Description:
NDC80 homolog, kinetochore complex component (S. cerevisiae)
Gene Alias:
HEC,HEC1,KNTC2,TID3,hsNDC80
Gene Name:
NDC80
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer:
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Recommend Usage:
ELISA (1:32000) Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Concentration:
0.5 mg/mL
Purification:
Antigen affinity purification
Form:
Liquid
Reactivity:
Human
Theoretical MW (kDa):
73.9
Host:
Goat
Sequence:
C-YEKKATLIKSSEE
Immunogen:
A synthetic peptide corresponding to human NDC80.
Product Description:
Goat polyclonal antibody raised against synthetic peptide of NDC80.