bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase,coenzyme A synthase,nucleotide binding protein,phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase
Gene Summary:
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM
Gene Description:
Coenzyme A synthase
Gene Alias:
DPCK,FLJ35179,NBP,PPAT,UKR1,pOV-2
Gene Name:
COASY
Storage Instruction:
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
Supplied Product:
Antibody pair set content: 1. Antibody pair for IP: rabbit polyclonal anti-COASY (300 ul) 2. Antibody pair for WB: mouse purified polyclonal anti-COASY (50 ug)
Quality Control Testing:
Immunoprecipitation-Western Blot (IP-WB) Immunoprecipitation of COASY transfected lysate using rabbit polyclonal anti-COASY and Protein A Magnetic Bead (), and immunoblotted with mouse purified polyclonal anti-COASY.
Reactivity:
Human
Product Description:
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.