This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Store the kit at 4°C. For long term storage, please store at -20°C.
Quality Control Testing:
Standard curve The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Reactivity:
Human
Limit of Detection:
0.25 ng/ml
Calibration Range:
0.281 to 18 ng/mL
Product Description:
CFH (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CFH.