The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Gene Description:
chemokine (C motif) receptor 1
Gene Alias:
CCXCR1,GPR5
Gene Name:
XCR1
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Instruction:
Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer:
In PBS (0.09% sodium azide)
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 ug/mL) The optimal working dilution should be determined by the end user.
Purification:
Immunoaffinity purification
Form:
Liquid
Specificity:
C-terminal cytoplasmic domain of human .
Reactivity:
Human
Host:
Rabbit
Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to human XCR1.
Product Description:
Rabbit polyclonal antibody raised against synthetic peptide of XCR1.