This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants
Gene Description:
corticotropin releasing hormone receptor 1
Gene Alias:
CRF-R,CRF1,CRFR1,CRH-R1h,CRHR,CRHR1f
Gene Name:
CRHR1
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage Instruction:
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer:
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Recommend Usage:
ELISA (1:32000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Concentration:
0.5 mg/mL
Purification:
Antigen affinity purification
Form:
Liquid
Reactivity:
Human, Mouse
Theoretical MW (kDa):
47.7
Host:
Goat
Sequence:
C-NEEKKSKVHYH
Immunogen:
A synthetic peptide corresponding to amino acids 107-117 of human CRHR1.
Product Description:
Goat polyclonal antibody raised against synthetic peptide of CRHR1.