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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
SC1
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
839707-37-8
- 规格:
10 mM * 1 mL/1 mg/2 mg/5 mg/10 mg/25 mg/50 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1199.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥459.0 |
| 规格: | 2 mg | 产品价格: | ¥650.0 |
| 规格: | 5 mg | 产品价格: | ¥990.0 |
| 规格: | 10 mg | 产品价格: | ¥1750.0 |
| 规格: | 25 mg | 产品价格: | ¥3500.0 |
| 规格: | 50 mg | 产品价格: | ¥5463.0 |
MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
Pluripotin
CAS No. : 839707-37-8
MCE 国际站:Pluripotin
产品活性:Pluripotin 是 ERK1 和 RasGAP 的双重抑制剂,KD 分别为 98 nM 和 212 nM。Pluripotin 还抑制 RSK1,RSK2,RSK3 和 RSK4,IC50 分别为 0.5,2.5,3.3 和 10.0 μM。
研究领域:MAPK/ERK Pathway | Stem Cell/Wnt
作用靶点:Ribosomal S6 Kinase (RSK) | ERK
In Vitro: Pluripotin (SC-1) inhibits Abl1, p70S6K, PLK2, RSK1, RSK2, RSK3, RSK4 with IC50s of 0.005, 1.4, 2.2, 0.5, 2.5, 3.3, 10.0 µM,respectively. Pluripotin (SC-1) decreases cell growth for 7 colon tumor cell lines. After a five day exposure to 0.1 µM SC-1, the seven colon tumor lines are evaluated for changes in cell number and viability. There is a statistically significant decrease in cell number but >95% viability.
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