- ￥5300
- GeneTex
- 美国
- GTX50200
- 2025年11月07日
- WB
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around phosphorylation site of serine 280 (V-T-S(p)-G-G) derived from human Chk1.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Polyclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX50200
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
Chk1 (phospho Ser280)
- 抗体英文名：
Chk1 (phospho Ser280) antibody
- 抗体名：
Chk1 (phospho Ser280) 抗体
- 规格：
100 μl
WB analysis of extracts from HepG2 cells untreated or treated with UV using GTX50200 Chk1 (phospho Ser280) antibody.
WB analysis of extracts from A2780 cells treated with calf intestinal phosphatase (CIP) using GTX50200 Chk1 (phospho Ser280) antibody.
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文献和实验Mammalian CHK1 is a Ser/Thr effector kinase that plays critical roles in the DNA damage-activated cell cycle checkpoint signaling pathway downstream of ATR (ATM and Rad3-related protein kinase). This chapter is focused on describing an assay
Methods for Studying Checkpoint Kinases Chk1
. Phospho-specific antibodies can be used to detect these activating phosphorylations, and this provides a simple and sensitive marker of Chk1 activation.
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
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