- ￥2310 - 23910
- Sino Biological
- 北京
- 11081-H08H
- 2026年01月26日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃ to -80℃
- 保质期：
12个月
- 英文名：
Recombinant Human Insulin Receptor/INSR Protein(ECD,long isoform,His Tag)
- 库存：
99
- 供应商：
北京义翘神州科技股份有限公司
- 规格：
1.00 mg/50.00 µg/100.00 µg
| 规格： | 1.00 mg | 产品价格： | ￥23910.0 |
|---|---|---|---|
| 规格： | 50.00 µg | 产品价格： | ￥2310.0 |
| 规格： | 100.00 µg | 产品价格： | ￥3870.0 |
蛋白名称：Human Insulin Receptor / INSR / CD220 Protein (ECD,long isoform, His Tag)
蛋白构建：A DNA sequence encoding the human INSR isoform long (NP_000199.2) extracellular domain (Met1-Lys956) was expressed fused with a polyhistidine tag at the C-terminus.
表达宿主：HEK293 Cells
蛋白纯度：> 95 % as determined by SDS-PAGE
蛋白活性：0
蛋白内毒素：< 1.0 EU per μg of the protein as determined by the LAL method
预测N端：His 28 & Ser 763
蛋白分子量：The secreted recombinant human INSR isoform long consists of 940 amino acids and has a predicted molecular mass of 107 (83+24) kDa. As a result of glycosylation, the apparent molecular mass of human INSR is approximately 110-125 kDa & 40-45 kDa, corresponding to the α subunit and the ECD of β subunit respectively in SDS-PAGE under reducing conditions.
蛋白NP号：NP_000199.2
蛋白氨基酸序列：Met1-Lys956
蛋白标签：C-His
蛋白保存条件：Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验Quantification of the Level of Insulin Gene Expression
). Such commercially available kits can also be used to isolate poly-A+ RNA (mRNA) only, which assists in decreasing background signals. To investigate both rapid and long-term effects on insulin gene expression, advances in reporter gene technology have allowed
A Mouse Model of Diet-Induced Obesity and Insulin Resistance
and adaptation. Therefore, it is difficult ascertain the exact mechanisms for this long-term process in humans. To circumvent some of these issues, several surrogate models are available, including murine genetic loss-of-function mutations, transgenic gain
Insulin and Growth Factor Signaling: Effects on Drug-Metabolizing Enzymes
Expression of drug-metabolizing enzymes may be altered in response to development, aging, gender, genetics, nutrition, pregnancy, disease states such as diabetes, long-term alcohol consumption, and inflammation, and by xenobiotics
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