- ￥3000 - 3999
- Abbiotec
- 美国
- 250894
- 2025年12月04日
- E, WB, IHC
- Rabbit
- H, M, R
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Trk A/B/C.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Trk A/B/C.
- 目录编号：
250894
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB, IHC
- 浓度：
见详细说明信息
- 靶点：
Trk A/B/C
- 抗体英文名：
Trk A/B/C Antibody
- 抗体名：
Trk A/B/C Antibody
- 规格：
0.1 mg
Trk A/B/C Antibody产品详细介绍：
| 产品名称： | Trk A/B/C Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 250894 |
| 规格： | 0.1 mg |
| 产品描述： | The Trk family of nerve growth factor receptors includes Trk A, Trk B and Trk C. The prototype member of this gene family, Trk A encodes a 140-kDa cell surface receptor (gp140) expressed in neurons of the sensory spinal and cranial ganglia of neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk A in neural cell lines and embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, neurotrophin-3 (NT-3), but not NGF, can induce tyrosine phosphorylation of Trk B gp 145. Trk C, the third member of the Trk receptor family, encodes a 140-kDa protein, Trk C gp 140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3. An additional component of the Trk receptor complex, NGFR p 175 , binds to neurotrophic factor with low affinity but is required for efficient signaling. Defects in Trk A are a cause of congenital insensitivity to pain with anhidrosis (CIPA). CIPA is characterized by a congenital insensitivity to pain, anhidrosis (absence of sweating), absence of reaction to noxious stimuli, self-mutilating behavior, and mental retardation. This rare autosomal recessive disorder is also known as congenital sensory neuropathy with anhidrosis or hereditary sensory and autonomic neuropathy type IV or familial dysautonomia type II. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Trk A/B/C. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IHC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名： | High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; p140-TrkA; Trk-A; NTRK1; TRK; NT-3 growth factor receptor; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase; GP145-TrkC; Trk-C; NTRK3; TRKC; BDNF/NT-3 growth factors receptor; Neurotrophic tyrosine kinase receptor type 2; TrkB; TrkB tyrosine kinase; GP145-TrkB; Trk-B; GP145; NTRK2 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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