Product nameNecrostatin-1
Description
Potent, specific necroptosis inhibitor
Biological descriptionPotent, specific necroptosis inhibitor (EC50 = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro(EC50 = 182 nM). Caspase independent, programmed necrosis pathway.
Purity> 99%
Properties
Chemical name5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
Molecular weight259.33
Chemical structure
Molecula formulaC13H13N3OS
CAS Number4311-88-0
PubChem identifier2828334
Storage instructionsStore at -20°C. Store under Desiccating conditions. The product can be stored for up to 12 months.