简介: 货 号:LC1-R-1234 名 称:细胞周期蛋白B激酶抑制剂 别 名:Roscovitine Free Base C A S :186692-46-6 分子量:354.45 分子式:C19H26N6O 纯 度:HPLC/TLC:>99% 说 明:Storage: Store at or below -20 ºC. Solubility: Prepare initial stock solutions in DMSO (soluble at 200 mg/mL) or ethanol (soluble at 200 mg/mL) for in vitro use; solubility in water is low. Appearance: White to off-white powder. Disposal: A. 文 献:Roscovitine is a potent inhibitor of p34cdc2 (IC50 = 0.2 µM). Also inhibits p33cdk2 and p33cdk5. Havlicek, L., et al. "Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds." J. Med. Chem. 40: 408-412 (1997).