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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
南京赛泓瑞
- 检测范围:
13.72-10000pg/mL The standard curve concentrations used for the CLIA’s were 10000pg/mL, 3333.33pg/mL, 1111.11pg/mL, 370.37pg/mL, 123.46pg/mL, 41.15pg/mL, 13.72pg/mL
- 检测方法:
CLIA
- 应用:
CLIA
- 适应物种:
Homo sapiens (Human)
- 样本:
Serum, plasma, tissue homogenates and other biological fluids
- 规格:
48T/96T
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文献和实验一氧化氮合酶组织化学染色法 一氧化氮合酶(nitrfic oxides synthase,NGS)是一种连接酶,能催化前体物质L精氨酸生成L瓜氨酸和一氧化氮(NO)。NO是中枢和外周神经系统中的一种神经递质,活细胞间信使和内皮源性松弛血管的介质,在神经、心血管及免疫系统中有广泛的作用。NO极不稳定。易于扩散游离,半衰期短,不易检测。因NOS是合成NO的关键酶,故通常通过检测NOS的活性来评估NO的分布和功能。NOS有3种异构型,即神经型NOS(neuronal NOS,nNOS)、内皮
一氧化氮合酶的亚型 (eNOS , Ki = 700 nM; iNOS , Ki = 3.9 µM; nNOS , Ki = 650 nM) 。豚鼠肺动脉中抑制组织胺和乙酰胆碱诱导的去甲肾上腺素收缩的放松。目前发现参与 NO 正常生理或病理过程的有三种类型的 NOS ,分别是:nNOS (neuronal/Type I/NOS-1/bNOS) , eNOS (endothelial/Type III/NOS-3) 和 iNOS
The Use of Propidium Iodide to Assess Excitotoxic Neuronal Death in Primary Mixed Cortical Cultures
(nNOS). Thus, for the purposes of this chapter, the insult used to induce cell death will be various concentrations of NMDA and the compound used to demonstrate neuroprotection will be the nonspecific NOS inhibitor N ω-nitro-L
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