- ￥413 - 5330
- TargetMol
- 美国
- T6343
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Geldanamycin
- 库存：
10
- 供应商：
TargetMol
- CAS号：
30562-34-6
- 规格：
50 mg/10 mg/1 mg/5 mg/100 mg/25 mg/1 mL
| 规格： | 50 mg | 产品价格： | ￥3790.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥1630.0 |
| 规格： | 1 mg | 产品价格： | ￥413.0 |
| 规格： | 5 mg | 产品价格： | ￥987.0 |
| 规格： | 100 mg | 产品价格： | ￥5330.0 |
| 规格： | 25 mg | 产品价格： | ￥2720.0 |
| 规格： | 1 mL | 产品价格： | ￥1280.0 |
Product Introduction
Bioactivity
英文名:Geldanamycin
描述:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
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文献和实验Assays for HSP90 and Inhibitors
of HSP90 inhibitors have already been identified. These include the benzoquinone ansamycin natural product geldanamycin and its analog, 17-allylamino-17-demethoxy-geldanamycin (17AAG), together with the chemically dissimilar natural product radicicol
GPC Spin Column HPLCESI-MS Methods for Screening Drugs Noncovalently Bound to Proteins
are fully described. The GPC spin column HPLC–ESI-MS methodology for screening of drugs non-covalently bound to proteins is illustrated for the non-covalent binding of geldanamycin with Hsp90cat protein.
More Than One Way to Die: Methods to Determine TNF-Induced Apoptosis and Necrosis
apoptotically, because triggering of Fas in L929sAhFas cells leads to apoptosis. Moreover, TNFR-1-induced necrosis can be reverted to apoptosis when cells are pretreated with geldanamycin, an Hsp90 inhibitor. In contrast, addition of caspase-inhibitors (zVAD-fmk
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