In Vitro: L67 (10, 15 μM; 24 h) promotes nuclear DNA damage and (0-50 μM) increases the level of mSOX by inhibiting mitochondrial LigIIIα in HeLa cells. ?L67 (10 μM; 24 h) induces changes in mitochondrial function that cause a reduction in OCR and mitochondrial DNA, and abnormal mitochondrial morphology in HeLa. ?L67 (10, 100 μM; 24 h) induces apoptosis in cancer cells. ?L67 (0-30 μM; 24 h) selectively induces cell death in cancer cells by activating a caspase 1-dependent apoptotic pathway.