- 询价
- XY-Bioscience
- 中国/美国/德国
- XYB988Hu02
- 2025年07月16日
- WB, ICC, IHC-P, IHC-F, ELISA
- Rabbit，兔
- 见说明书
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
见说明书
- 亚型：
见说明书
- 形态：
液态/粉末
- 保存条件：
-20oC
- 克隆性：
多克隆
- 标记物：
未标记
- 适应物种：
见说明书
- 宿主：
Rabbit，兔
- 应用范围：
WB, ICC, IHC-P, IHC-F, ELISA
- 浓度：
200ug/ml
- 靶点：
见说明书
- 抗体英文名：
Polyclonal Antibody to Toll Like Receptor 1 (TLR1)
- 抗体名：
Toll样受体1(TLR1)多克隆抗体
| Organism species | Homo sapiens (Human) |
| Product No. | XYB988Hu02 |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunoglobulin Type | IgG |
| Purification | Affinity Chromatography |
| Applications | WB, ICC, IHC-P, IHC-F, ELISA |
| Concentration | 200ug/ml |
| UOM | 100ug |
| Conjugate | No Conjugate |
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-1:5000
Optimal working dilutions must be determined by end user.
containing 0.02% NaN3, 50% glycerol.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control. Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol, BPB 0.01%, NaN3 0.02%.
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文献和实验Expression Analysis of the Toll-Like Receptors in Human Peripheral Blood Mononuclear Cells
Toll-like receptors (TLRs) are key regulators of the innate and adaptive immune response to bacterial, viral, and fungal pathogens. To date, 10 human TLRs and 13 mouse TLRs have been identified and they exhibit tissue-specific mRNA/protein
对“表面Toll样受体（TLRs）”（先天免疫系统的跨膜蛋白，能够识别来自微生物的分子）的一个亚组进行刺激，被发现能够通过线粒体通道诱导可以杀菌的活性氧的生成。当“细菌”TLRs（TLR1、2和4）结合到一个配体上时，它们促使线粒体进入巨噬细胞的吞噬体，诱导“线粒体活性氧”（mROS）含量的增加。这项工作表明mROS是抗菌反应的重要成分，同时也进一步确定了线粒体在先天免疫信号作用中的核心作用。
of TLR2 can form functional pairs with TLR6 and TLR1, leading to signal transduction and cytokine gene expression. All TLRs activate signalling pathways that are similar to those activated by IL-1, because they share a Toll/IL-1R homology domain
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