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文献和实验Assessment of Insulin Secretion in the Mouse
. 1 ). The mouse synthesizes two molecular forms of insulin and C-peptide, which are identical to their respective rat counterparts ( 5 ). The two rodent insulins, designated insulin I and II, are present at a ratio of 1∶3 in the mouse and 4∶1 in the rat
A Mouse Model of Diet-Induced Obesity and Insulin Resistance
-of-function mutations, polygenic models, and different environmental exposure models. The mouse model of diet-induced obesity has become one of the most important tools for understanding the interplay of high-fat Western diets and the development of obesity
Analysis of Insulin and Insulin-Like Growth Factor-I Receptors in Neural Tissues
A variety of biochemical and physiological studies in recent years have made it clear that the brain possesses specific receptors and puta- tive signal transduction pathways for insulin and the insulin-like growth factors (IGF-I and IGF
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