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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
抗 Nivolumab 抗体 6G5 单克隆抗体(鼠源)
- 抗体英文名:
Anti Nivolumab Antibody 6G5 mAb Mouse
- 靶点:
Nivolumab 抗体
- 浓度:
0.5mg/mL(常规浓度,以官方说明书为准)
- 应用范围:
ELISA、免疫印迹、免疫组化、流式细胞术
- 宿主:
小鼠(Mouse)
- 适应物种:
通用
- 保质期:
- 20℃可稳定保存 半 年
- 抗原来源:
抗 Nivolumab 抗体 6G5 克隆
- 级别:
科研级
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 标记物:
无(Unconjugated)
- 克隆性:
单克隆(Monoclonal)
- 保存条件:
-20℃,可稳定保存 半 年
- 形态:
液体(Liquid)
- 亚型:
Mouse IgG
- 免疫原:
抗 Nivolumab 抗体 6G5 克隆
- 规格:
40μg
| Specificity | The product is specific for Nivolumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody We, A01847-40, Anti- Nivolumab Antibody (8G6G3D8), mAb, Mouse. |
| Host Species | Mouse |
| Immunogen | Nivolumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Buffer | lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for 1 year at -20℃ from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8℃ or for 12 months at -20℃ or below. Avoid freeze/thaw cycles. |
| Purification | Protein A affinity column |
| Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Clone ID | 6G5 |
| Note | We can customize this product per customer's request including product size, buffer components, etc. |
| Target Background | Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.We Anti-Nivolumab Antibody (6G5), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Nivolumab. |
| Synonyms | Mouse monoclonal to Opdivo |
Anti-Nivolumab Antibody 抗体、抗纳武利尤单抗抗体、纳武利尤单抗抗体、6G5 抗体、鼠源抗体、单克隆抗体、抗药抗体、WB 抗体、IHC 抗体、IF 抗体、ELISA 抗体
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
4-Hydroxy-2-Nonenal (4-HNE) Staining by Anti-HNE Antibody
using an anti-4-HNE monoclonal antibody (MAb) (6 –8 ) and labeled goat anti-mouse IgG antibody (9 ).
相关专题单克隆抗体 单克隆抗体问世以来,在临床诊断、治疗与预防等方面发挥了巨大的作用。但是常用的鼠源单克隆抗 体具有较强的免疫原性,在临床反复应用中会引起人抗鼠抗体(human anti -mouse antibody,HAMA)反应, 导致半衰期缩短,治疗效果减弱。鼠源抗体人源化是指利用DNA 重组技术和蛋白质工程技术,对抗体基 因进行重组,在保留鼠源抗体对抗原有效结合部位的同时,最大限度地降低非结合部位的鼠源性。这种通 过重组基因所表达
技术资料




