相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
抗 Bevacizumab 抗体 4H1 单克隆抗体(鼠源)
- 抗体英文名:
Anti Bevacizumab Antibody 4H1 mAb Mouse
- 靶点:
Bevacizumab 抗体
- 浓度:
0.5mg/mL(常规浓度,以官方说明书为准)
- 应用范围:
ELISA、免疫印迹、免疫组化、流式细胞术
- 宿主:
小鼠(Mouse)
- 适应物种:
通用
- 保质期:
- 20℃可稳定保存 半 年
- 抗原来源:
抗 Bevacizumab 抗体 4H1 克隆
- 级别:
科研级
- 库存:
现货
- 供应商:
上海经科化学科技有限公司
- 标记物:
无(Unconjugated)
- 克隆性:
单克隆(Monoclonal)
- 保存条件:
-20℃,可稳定保存 半 年
- 形态:
液体(Liquid)
- 亚型:
Mouse IgG
- 免疫原:
抗 Bevacizumab 抗体 4H1 克隆
- 规格:
40μg
| Specificity | The product is specific for Bevacizumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody We, A01976-40, Anti-Bevacizumab Antibody (6C3), mAb, Mouse. |
| Host Species | Mouse |
| Immunogen | Bevacizumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Buffer | lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for 1 year at -20℃ from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8℃ or for 12 months at -20℃ or below. Avoid freeze/thaw cycles. |
| Purification | Protein A affinity column |
| Isotype | Mouse IgG1 |
| Clonality | Monoclonal |
| Clone ID | 4H1 |
| Note | We can customize this product per customer's request including product size, buffer components, etc. |
| Target Background | Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of a number of types of cancers and a specific eye disease. Bevacizumab binds to a continuous epitope in VEGF, preventing interaction of VEGF with VEGFR on the surface of endothelial cells. It can be used to inhibit solid tumour growth and metastasis by weakening tumour angiogenesis.Anti-Bevacizumab Antibody (4H1), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Bevacizumab. |
| Synonyms | Mouse monoclonal to Avastin |
Anti-Bevacizumab Antibody 抗体、抗贝伐珠单抗抗体、贝伐珠单抗抗体、4H1 抗体、鼠源抗体、单克隆抗体、抗药抗体、WB 抗体、IHC 抗体、IF 抗体、ELISA 抗体
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验相关专题单克隆抗体 单克隆抗体问世以来,在临床诊断、治疗与预防等方面发挥了巨大的作用。但是常用的鼠源单克隆抗 体具有较强的免疫原性,在临床反复应用中会引起人抗鼠抗体(human anti -mouse antibody,HAMA)反应, 导致半衰期缩短,治疗效果减弱。鼠源抗体人源化是指利用DNA 重组技术和蛋白质工程技术,对抗体基 因进行重组,在保留鼠源抗体对抗原有效结合部位的同时,最大限度地降低非结合部位的鼠源性。这种通 过重组基因所表达
和Milstein建立了体外细胞融合技术,获得了免疫小鼠脾细胞与骨髓瘤细胞融合的杂交瘤细胞,大规模地制备出高特异性的单克隆抗体(monoclonal antibody,简称单抗)。此后,单抗在理论和实践上的应用,成了解决生物学、医学等诸多重大问题的重要手段。然而其中仍有问题有待解决,例如在体内应用时,作为异源蛋白的单抗会引起人抗小鼠抗体反应(human anti-mouse antibody response,HAMA)。随着DNA操作和基因工程技术的发展,使得人们已有可能对抗体基因进行拆装和改建,发展出种种
Cell Fusion Protocol for Cell Fusion General Fusion Protocol Fusion of Mouse, Rat, or Hamster Cell Immunization Protocol for Monoclonal Antibody Production Cloning by Limiting Dilution of Hybridoma Limiting Dilutions Protein A Purification
技术资料









