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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
- 保质期:
参照说明书可保存1-2年
- 英文名:
TNF-alpha peptide
- 库存:
一定量库存
- 供应商:
华拓生物
- 规格:
0.1 mg
| 产品名称: | TNF-alpha peptide |
| 产品链接: | http://www.abbiotec.com/peptides/tnf-alpha-peptide |
| 货号: | 300124 |
| 规格: | 0.1 mg |
| 产品描述: | Tumor necrosis factor alpha (TNF-alpha) is a cytokine that binds to the TNF-R1 and TNF-R2 receptors. TNF-alpha is mainly secreted by macrophages and induces cell death of certain tumor cell lines. It is a potent pyrogen causing fever by direct action or by stimulation of IL-1 secretion, and therefore found in cachexia accompanying diverse cancers and infections. Genetic variations in TNF are associated with susceptibility to psoriatic arthritis and to HBV infection. |
| 序列: | The synthetic peptide used to raise the antibody Cat. No. 251900 is selected from a sequence within the C-term region of human TNF-alpha. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分子式: | C171H264N44O54S1 |
| 分子量: | 3832.5 g/mol |
| 纯度: | Purity > 80% by HPLC |
| 别名: | Tumor necrosis factor; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; TNF; TNFA; TNFSF2 |
| 形态: | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| 溶解方法: | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法: | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
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Two dimensional peptide mapping
This specfic protocol is the latest incarnation of peptide mapping procedures that have been developed here in the TVL/MBVL of the Salk Institute over the last 20 years. Wade Gibson developed the first peptide mapping protocol
【求助】有什么办法可以阻滞LPS刺激的TNF-alpha分泌?
sonny_zan 我实验的关键步骤,现在就是不知道有什么办法可以阻滞LPS刺激后PBMC分泌TNF-alpha,考虑过用p38 MAPK抑制剂SB203580,后来查到一篇文献说SB203580对LPS刺激后p38 MAPK的活性影响甚微或无。 请各位大侠给点意见啦!我快急死了~~~ xiongran 拿抗体把PBMC表面的TLR4封闭掉试试看! pureclear 可以考虑
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